Dr. Eng.Paulina Błaszkiewicz

Ph.D. in Engineering and Technical Sciences in the discipline of Materials Engineering, Poznań University of Technology

AMU Research Portal Profile

Research interests:

  • Synthesis and Functionalization of Metal Nanoparticles
  • Nanoparticle-Dye Hybrid Systems
  • Photodynamic/Photothermal Therapy

Selected Publications: 

  • D. Ziental, P. Błaszkiewicz, J. Długaszewska, E. Güzel, A. Dudkowiak, Ł. Sobotta, Modified gold nanoparticles modulated fluorescence and singlet oxygen generation of pheophorbide a as an effective platform for photodynamic therapy against Staphylococcus aureus, European Journal of Inorganic Chemistry, 2024 (IF=2.551; pkt. MEiN=70)
  • P. Talarska, P. Błaszkiewicz, A. Kostrzewa, P. Wirstlein, M. Cegłowski, G. Nowaczyk, A. Dudkowiak, B. O. Grabarek, P. Głowacka-Stalmach, A. Szarpak, J. Żurawski, Effects of Spherical and Rod-like Gold Nanoparticles on the Reactivity of Human Peripheral Blood Leukocytes, Antioxidants, 2024, 13, 157 (IF=7.675; pkt. MEiN=100)

Projects:

SONATINA 7: Hybrid nanocomposites based on gold nanoparticles as promising photoactive materials for combined photothermal/photodynamic therapy – HyPhoto2 Supervising institution: National Science Centre
Project manager: Dr. Eng. Paulina Błaszkiewicz
Budget: PLN 924,228
Start date: 01-12-2023
Duration: 3 years
Contract number: UMO-2023/48/C/ST4/00067

Abstract: 

The development of methods and possibilities of producing nanomaterials implies progress in the field of improving and applying new medical procedures. Interdisciplinary research is being conducted on many levels to find effective diagnostic and/or therapeutic methods using, among others, metallic nanoparticles. Determining the photophysical properties of nanoparticles and examining their interactions with biological material provides important information that allows the creation of increasingly better drug or vaccine delivery systems and the identification of potential side effects. The HyPhoto2 project proposes conducting basic research for systems produced on the basis of gold nanoparticles, which in the area of ​​the so-called therapeutic window (above 650 nm) exhibit plasmon resonance, associated with the interaction of light with free electrons of metallic nanostructures. The interaction of surface plasmons with the dye may affect the efficiency of photophysical processes, important from the point of view of potential applications of metal-dye hybrid systems in photomedicine. The research results will provide important information on the photophysical properties of the tested, functionalized nanoparticles and their hybrid systems and will indicate the potential for their use in biomedical applications.