Dr. Eng.Dorota Katarzyna Flak
Ph.D. in Chemical Sciences, Faculty of Materials Science and Ceramics, Department of Analytical Chemistry, AGH University of Science and Technology in Kraków, 2013
Researach interests:
- Synthesis and (bio-)functionalization of nanomaterials and their application in biomedicine (drug delivery and bioimaging agents)
- Nanomaterials for biomedical applications: metal oxides, quantum dots, lipid nanoparticles, hybrid nanoparticles
- Nanocrystalline semiconductor materials: synthesis and modification of their surface properties, optical and electrical properties, electronic structure.
Project:
MINIATURA 1 (NCN): „Functionalization of Graphene Quantum Dots with Cancer Cell-Specific Ligands”.
Selected Publications:
- M. Diak, D. Flak, M. Jarek, Ł. Przysiecka, G. Nowaczyk, Aqueous phase transfer of near-infrared ZnCuInS2/ZnS quantum dots: Synthesis and characterization, Biomaterials Advances, 2025, 166, 214083.
- K. Dydak, T. Zalewski, M. Kempka, P. Florczak, G. Nowaczyk, Ł. Przysiecka, J. Jagielski, B. Loppinet, M. Banaszak and D.K. Flak, Nanoassemblies with Gd-chelating lipids (GMO@DTPA-BSA-Gd) as potential new type of high molecular weight contrast agents, J. Mater. Chem. B, 2024, 12, 12017-12029.
- G. Nowaczyk, M. Kempka, B. Wereszczyńska, D. Flak, J. Gapiński, Viscoelasticity, morphology, and molecular diffusion in structurally controlled ternary poly(acrylic acid) and nonionic surfactant-based hydrogels, Polymer Testing, 2024 137,108505.
- D. Flak, T. Zalewski, K. Fiedorowicz, Ł. Przysiecka, M. Jarek, A. Klimaszyk, M. Kempka, A. Zimna, N. Rozwadowska, J. Avaro, M. Liebi, G. Nowaczyk, Hybrids of manganese oxide and lipid liquid crystalline nanoparticles (LLCNPs@MnO) as potential magnetic resonance imaging (MRI) contrast agents, J. Mat. Chem. B, 2023, 11(36), 8732-8753.
- J. Jagielski, Ł. Przysiecka, D. Flak, M. Diak, Z. Pietralik-Molińska, M. Kozak, S. Jurga, G. Nowaczyk, Comprehensive and comparative studies on nanocytotoxicity of glyceryl monooleate- and phytantriol-based lipid liquid crystalline nanoparticles, J. Nanobiotechnol., 2021, 19(1), 168.
- O. Ivaschenko, Ł. Przysiecka, B. Peplińska, D. Flak, E. Coy, M. Jarek, T. Zalewski, A. Musiał, S. Jurga, Organic–Inorganic Hybrid Nanoparticles Synthesized with Hypericum perforatum Extract: Potential Agents for Photodynamic Therapy at Ultra-low Power Light, ACS Sustain. Chem. Eng., 2021, 9, (4), 1625–1645.
- D. Flak, V. Adamski, G. Nowaczyk, K. Szutkowski, M. Synowitz, S. Jurga, J. Heldt-Feindt, AT101-loaded cubosomes as an alternative for improved glioblastoma therapy, Int. J. Nanomed., 2020, 15:7415-7431.
- D. Flak, Ł. Przysiecka, G. Nowaczyk, B. Scheibe, M. Kościński, T. Jesionowski, S. Jurga, GQDs-MSNs nanocomposite nanoparticles for simultaneous intracellular drug delivery and fluorescent imaging, J. Nanopart. Res., 2018, 20:306.
- O. Ivashchenko, B. Peplińska, J. Gapiński, D. Flak, M. Jarek, K, Załęski, G. Nowaczyk, Z. Pietralik, S. Jurga, Silver and ultrasmall iron oxides nanoparticles in hydrocolloids: effect of magnetic field and temperature on self-organization, Sci. Rep., 2018, 8: 4041.
- D. Flak, L. Yate, G. Nowaczyk, S. Jurga, Hybrid ZnPc@TiO2 nanostructures for targeted photodynamic therapy, bioimaging and doxorubicin delivery, Mat. Sci. Eng. C, 78, 2017, 1072–1085.
- D. Flak, L.E. Coy, G. Nowaczyk, L. Yate, S. Jurga, Tuning of photodynamic efficiency of TiO2 nanotubes against HeLa cancer cells by Fe-doping, RSC Adv., 5, 2015, 85139.
- D. Flak, A. Braun, B. Mun, et al., Spectroscopic assessment of the role of hydrogen on surface defects, on the electronic structure and transport properties of TiO2, ZnO and SnO2 nanoparticles, Phys. Chem. Chem. Phys., 2013, 15, 1417-1430