Dr. Patrick Perrigue

Ph.D in Cellular and Molecular Biology, City of Hope National Medical Center in Duarte, California, USA, 2013
Research interests: 
  • Chromatin regulation in cellular senescence and cancer.
  • Stem cell biology – including studies focusing on plasticity, regeneration, reprogramming.
  • Application of nanocarriers in biomedicine.
Selected publications: 
  • Perrigue, P.M.; Rakoczy, M.; Pawlicka, K.P.; Belter, A.; Giel-Pietraszuk, M.; Naskręt-Barciszewska, M.; Barciszewski, J.; Figlerowicz, M. Cancer stem cell-inducing media activates senescence reprogramming in fibroblasts. Cancers (Basel). 2020.
  • Barciszewska, A.M.; Giel-Pietraszuk, M.; Perrigue, P.M.; Naskręt-Barciszewska, M. Total DNA Methylation Changes Reflect Random Oxidative DNA Damage in Gliomas. Cells 2019.
  • Li, Z.; Oganesyan, D.; Mooney, R.; Rong, X.; Christensen, M.J.; Shahmanyan, D.; Perrigue, P.M.; Benetatos, J.; Tsaturyan, L.; Aramburo, S.; et al. L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells. Stem Cell Reports 2016.
  • Perrigue, P.M.; Najbauer, J.; Barciszewski, J. Histone demethylase JMJD3 at the intersection of cellular senescence and cancer. Biochim. Biophys. Acta - Rev. Cancer 2016.
  • Perrigue, P.M.; Silva, M.E.; Warden, C.D.; Feng, N.L.; Reid, M.A.; Mota, D.J.; Joseph, L.P.; Tian, Y.I.; Glackin, C.A.; Gutova, M.; et al. The histone demethylase Jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. Mol. Cancer Res. 2015.

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