This study is devoted to the evaluation of the influence of phosphate dopants on the reactivity of Nb₂O₅-based nanomaterials in the combined catalytic activation of H₂O₂ and the elimination of methylene blue (MB) from an aqueous solution via adsorption and chemical degradation. For this purpose, several niobia-based catalysts doped with various amounts of phosphate were prepared by a facile hydrothermal method and subsequent calcination. Phosphate doping was shown to strongly enhance the ability of Nb₂O₅ to activate H₂O₂, as well as to adsorb and degrade MB. The most pronounced differences in the reactivity of the parent Nb₂O₅ and phosphate-doped samples were observed under strongly acidic conditions (pH ~ 2.4), at which the most active modified catalysts (Nb/P molar ratio = 5/1) was approximately 6 times more efficient in the removal of MB. The observed enhancement of reactivity was attributed to the increased generation of singlet oxygen ¹O₂, which was identified as the main oxidizing agent responsible for efficient degradation of MB. To our knowledge, it is the first report revealing that phosphate doping of Nb₂O₅ resulted in an improved activity of niobia in the adsorption and degradation of organic pollutants