NanoBioMedical Centre
Adam Mickiewicz University
in Poznań

Dr. Eng. Karolina Adrjanowicz

Degree: 
Ph.D. in Physics, University of Silesia, Poland (2012)
Research interests: 
  • Molecular dynamics in supercooled and glassy state of pharmaceuticals, biomolecules and polymers
  • Thermodynamic properties of supercooled liquids
  • Factors responsible for physical and chemical instability of glass-formers
  • Crystallization kinetics of supercooled liquid state at ambient and elevated pressure
  • Crystallization phenomena of supercooled liquids in confined geometry
Selected publications: 
  • K. Kaminski, K. Adrjanowicz, Z. Wojnarowska, M. Paluch, E. Kaminska, A. Kasprzycka, Do intermolecular interactions control crystallization abilities of glass forming liquids? The Journal of Physical Chemistry B 2011, 115(40), 11537–11547
  • K. Adrjanowicz, K. Kaminski, Z. Wojnarowska, M. Dulski L. Hawelek, S. Pawlus, M. Paluch, Dielectric Relaxation and Crystallization Kinetics of Ibuprofen at Ambient and Elevated Pressure, The Journal of Physical Chemistry B 2010, 114(19), 6579–6593.
  • Z. Wojnarowska, K. Adrjanowicz, P. Wlodarczyk, E. Kaminska, K. Kaminski, K. Grzybowska, R. Wrzalik, M. Paluch, K. L. Ngai, Broadband dielectric relaxation study at ambient and elevated pressure of molecular dynamics of pharmaceutical: indomethacin,  The Journal of Physical Chemistry B 2009, 113(37), 12536–12545.

Publications

The effect of hydrogen bonding propensity and enantiomeric composition on the dynamics of supercooled ketoprofen – dielectric, rheological and NMR studies

Physical Chemistry Chemical Physics, 2016, 18, 10585-10593
K. Adrjanowicz, K. Kaminski,, M. Tarnacka, K. Szutkowski, Ł. Popenda, G. Bartkowiak, M. Paluch
[Details]

Negative pressure vitrification of the isochorically confined liquid in nanopores

Physical Review Letters, 2015, 115, 265702
K. Adrjanowicz, K. Kamiński, K. Koperwas, M. Paluch
[Details]

The Improvement of the Dissolution Rate of Ziprasidone Free Base from Solid Oral Formulations

AAPS PharmSciTech, 2015, 16, 4, 922–933
D. Zakowiecki, K. Cal, K. Kaminski, K. Adrjanowicz, L. Swinder, E. Kaminska, G. Garbacz
[Details]

Effect of High Pressure on Crystallization Kinetics of van der Waals Liquid: An Experimental and Theoretical Study

Crystal Growth & Design, 2014, 14(5), 2097–2104
K. Adrjanowicz, A. Grzybowski, K. Grzybowska, J. Pionteck, M. Paluch
[Details]

Dynamic Glass Transition and Electrical Conductivity Behavior Dominated by Proton Hopping Mechanism Studied in the Family of Hyperbranched Bis-MPA Polyesters

Macromolecules, 2014, 47(16), 5798-5807
K. Adrjanowicz, K. Kaminski, M. Dulski, M. Jasiurkowska-Delaporte, K. Kolodziejczyk, M. Jarek, G. Bartkowiak, L. Hawelek, S. Jurga, M. Paluch
[Details]

Impact of low molecular weight excipient octaacetylmaltose on the liquid crystalline ordering and molecular dynamics in the supercooled liquid and glassy state of itraconazole

European Journal of Pharmaceutics and Biopharmaceutics, 2014, 88(3), 1094-1104
E. Kaminska, M. Tarnacka, K. Kolodziejczyk, M. Dulski, D. Zakowiecki, L. Hawelek, K. Adrjanowicz, M. Zych, G. Garbacz, K. Kaminski
[Details]

Enhancement of the Physical Stability of Amorphous Indomethacin by Mixing it with Octaacetylmaltose. Inter and Intra Molecular Studies

Pharmaceutical Research, 2014, 31(10), 2887-2903
E. Kaminska, K. Adrjanowicz, D. Zakowiecki, B. Milanowski, M. Tarnacka, L. Hawelek, M. Dulski, J. Pilch, W. Smolka, I. Kaczmarczyk-Sedlak, K. Kaminski
[Details]

Impact of Inter- and Intramolecular Interactions on the Physical Stability of Indomethacin Dispersed in Acetylated Saccharides

Molecular Pharmaceutics, 2014, 11 (8), 2935–2947
E. Kaminska, K. Adrjanowicz, M. Tarnacka, K. Kolodziejczyk, M. Dulski, E. U. Mapesa, D. Zakowiecki, L. Hawelek, I. Kaczmarczyk-Sedlak, K. Kaminski
[Details]

The kinetics of mutarotation in L-fucose as monitored by dielectric and infrared spectroscopy

The Journal of Chemical Physics 2014, 140, 215101
W. Kossack, W. K. Kipnusu, M. Dulski, K. Adrjanowicz, O. Madejczyk, E. Kaminska, E. U. Mapesa, M. Tress, K. Kaminski, F. Kremer
[Details]

Molecular dynamics of itraconazole confined in thin supported layers

RSC Advances, 2014, 4(54), 28432-28438
E. U. Mapesa, M. Tarnacka, E. Kamińska, K. Adrjanowicz, M. Dulski, W. Kossack, M. Tress, W. K. Kipnusu, K. Kamiński, F. Kremer
[Details]

High pressure polymerization of glycidol. Kinetics studies

Polymer, 2014, 55(8), 1984-1990
M. Tarnacka, T. Flak, M. Dulski, S. Pawlus, K. Adrjanowicz, A. Swinarew, K. Kaminski, M. Paluch
[Details]

Kinetics and Dynamics of the Curing System. High Pressure Studies

Macromolecules, 2014, 47(13), 4288–4297
M. Tarnacka, O. Madejczyk, M. Dulski, M. Wikarek, S. Pawlus, K. Adrjanowicz, K. Kaminski, M. Paluch
[Details]

Toward Better Understanding Crystallization of Supercooled Liquids under Compression: Isochronal Crystallization Kinetics Approach

Crystal Growth & Design, 2013, 13(11), 4648–4654
K. Adrjanowicz, A. Grzybowski, K. Grzybowska, J. Pionteck, M. Paluch
[Details]

Molecular dynamics of the Supercooled Pharmaceutical Agent Posaconazole Studied via Differential Scanning Calorimetry and Dielectric and Mechanical Spectroscopies

Molecular Pharmaceutics, 2013, 10(10), 3934–3945
K. Adrjanowicz, K. Kamiński, P. Włodarczyk, K. Grzybowska, M. Tarnacka, D. Zakowiecki, G. Garbacz, M. Paluch, S. Jurga
[Details]

Communication: Synperiplnar to antiperiplanar conformation changes as underlying the mechanism od Debye proces in supercooled ibuprofen

Journal of Chemical Physics, 2013, 139(11), 111103
K. Adrjanowicz, K. Kamiński, M. Dulski, T. Włodarczyk, G. Bartkowiak, Ł. Popenda, S. Jurga, J. Kujawski, I. Kruk, M. K. Bernard, M. Paluch
[Details]

A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition Mechanism

Molecular Pharmaceutics, 2013, 10(5), 1824-35
E. Kaminska, K. Adrjanowicz, K. Kaminski, P. Wlodarczyk, L. Hawelek, K. Kolodziejczyk, M. Tarnacka, D. Zakowiecki, I. Kaczmarczyk-Sedlak, J. Pilch, M. Paluch
[Details]

Comparative Study on the Molecular Dynamics of a Series of Polypropylene Glycols

Macromolecules, 2013, 46, 1973-1980
K. Kamiński, W. K. Kipnusu, K. Adrjanowicz, E. U. Mapesa, C. Iacob, M. Jasiurkowska-Delaporte, P. Włodarczyk, K. Grzybowska, M. Plauch, F. Kremer
[Details]

Dynamics in ferro- and antiferroelectric phases of a liquid crystal with fluorinated molecules as studied by dielectric spectroscopy

Liquid Crystals, 2013, 40(8), 1082-1088
L. Kolek, M. Massalska-Arodź, M. Paluch, K. Adrjanowicz, T. Rozwadowski, D. Majda
[Details]

Glassy dynamics and physical aging in fucose saccharides as studied by infrared- and broadband dielectric spectroscopy

Physical Chemistry Chemical Physics, 2013, 15, 20641-20650
W. Kossack, K. Adrjanowicz, M. Tarnacka, W. K. Kipnusu, M. Dulski, E. U. Mapesa, K. Kaminski, S. Pawlus, M. Paluch, F. Kremer
[Details]

Molecular dynamics of itraconazole at ambient and high pressure

Physical Chemistry Chemical Physics, 2013, 15, 20742-20752
M. Tarnacka, K. Adrjanowicz, E. Kaminska, K. Kaminski, K. Grzybowska, K. Kolodziejczyk, P. Wlodarczyk, L. Hawelek, G. Garbacz, A. Kocot, M. Paluch
[Details]

Mutarotation in biologically important pure L-fucose and its enantiomer

Journal of Physics: Condensed Matter, 2013, 25(37), 375101
P. Wlodarczyk, A. Cecotka, K. Adrjanowicz, K. Kaminski, M. Paluch
[Details]

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